Emulsifiable concentrate formulations of 2 insect growth regulator (IGR) benzoyl ureas (novaluron and diflubenzuron) and the pyrethroid cis-permethrin were individually bioassayed against late 3rd- or early 4th-stage larvae of susceptible Aedes aegypti. The emergence inhibition 50% were 0.038, 0.048, and 0.179 ppb for novaluron, diflubenzuron, and cis-permethrin, respectively. We also tested 1:1 (v:v) mixtures of cis-permethrin and benzoyl ureas. Emergence inhibition 50% for novaluron plus cis-permethrin and diflubenzuron plus cis-permethrin were 0.030 and 0.037, respectively, with combination indexes of 0.49 and 0.56, indicating a synergistic interaction between these insecticides. The percentage of larval mortality produced by 0.5 ppb of the mixtures of cis-permethrin and each IGR was compared to the addition of larval mortality produced in separated experiments by 0.25 ppb of each component, after 5, 9 and 13 days of continuous exposure. In all bioassays, the novaluron plus cis-permethrin mixture produced a significantly higher larvicidal effect (P < 0.05) compared with the individual contribution of each compound. The diflubenzuron plus cis-permethrin mixture showed significantly higher larval mortality (P < 0.05) compared with the contributive effect of each insecticide after 9 and 13 days of exposure, but there was no significant difference after 5 days of exposure.
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1 March 2007
SYNERGISM BETWEEN CIS-PERMETHRIN AND BENZOYL PHENYL UREA INSECT GROWTH REGULATORS AGAINST AEDES AEGYPTI LARVAE
VALERIA SFARA,
SUSANA A. DE LICASTRO,
HECTOR M. MASUH,
EMILIA A. SECCACINI,
RAUL A. ALZOGARAY,
EDUARDO N. ZERBA
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Journal of the American Mosquito Control Association
Vol. 23 • No. 1
March 2007
Vol. 23 • No. 1
March 2007
Aedes aegypti
diflubenzuron
novaluron
pyrethroids
synergism